Contrave is a weight loss medication. Used along with diet and exercise, Contrave can help people lose weight and keep weight off.

Contrave is a combination of two different medications: naltrexone and bupropion hydrochloride. It is approved to help obese adults with a body mass index (BMI) of 30 or greater or overweight adults with a BMI of 27 or greater who have at least one weight-related condition such as type 2 diabetes, high cholesterol, or high blood pressure.